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Bioisosteric design of conformationally restricted pyridyltriazole histamine H2-receptor antagonists Christopher A. Lipinski pp 1 - 6; DOI: 10.1021/jm00355a001 |
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.beta.-Adrenergic antagonists with multiple pharmacophores: persistent blockade of receptors Josef Pitha, Jan Milecki, Teresa Czajkowska, and John W. Kusiak pp 7 - 11; DOI: 10.1021/jm00355a002 |
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Adriamycin analogs. Preparation and biological evaluation of some novel 14-thiaadriamycins Ramakrishnan Seshadri, Mervyn Israel, and William J. Pegg pp 11 - 15; DOI: 10.1021/jm00355a003 |
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Mitomycin C and porfiromycin analogs with substituted ethylamines at position 7 Bhashyam S. Iyengar, Salah M. Sami, William A. Remers, William T. Bradner, and John E. Schurig pp 16 - 20; DOI: 10.1021/jm00355a004 |
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Potential radiosensitizing agents. 6. 2-Nitroimidazole nucleosides: arabinofuranosyl and hexopyranosyl analogs Masakazu Sakaguchi, Cynthia A. Larroquette, and Krishna C. Agrawal pp 20 - 24; DOI: 10.1021/jm00355a005 |
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Pyrrolopyrimidine nucleosides. 18, Synthesis and chemotherapeutic activity of 4-amino-7-(3-deoxy-.beta.-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine-5-carboxamide (3'-deoxysangivamycin) and 4-amino-7-(2-deoxy-.beta.-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine-5-carboxamide (2'-deoxysangivamycin) Tokumi Maruyama, Linda L. Wotring, and Leroy B. Townsend pp 25 - 29; DOI: 10.1021/jm00355a006 |
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Antiviral compounds. 1. Structure-activity relationship of some antiviral enediones derived from aldehydo sugars Eli Breuer, David Melumad, Shalom Sarel, Eva Margalith, and Ehud Katz pp 30 - 34; DOI: 10.1021/jm00355a007 |
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2-Acetylpyridine thiosemicarbazones. 5. 1-[1-(2-Pyridyl)ethyl]-3-thiosemicarbazides as potential antimalarial agents Daniel L. Klayman, John P. Scovill, Joseph F. Bartosevich, and Joseph Bruce pp 35 - 39; DOI: 10.1021/jm00355a008 |
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Bicyclic lactones derived from kainic acid as novel selective antagonists of neuroexcitatory amino acids Ora Goldberg, Alberto Luini, and Vivian I. Teichberg pp 39 - 42; DOI: 10.1021/jm00355a009 |
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Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties Bruno S. Huegi, Anton M. Ebnoether, Erwin Rissi, Fulvio Gadient, Daniel Hauser, Dietmar Roemer, Heinz H. Buescher, and Trevor J. Petcher pp 42 - 50; DOI: 10.1021/jm00355a010 |
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Analogs of aminoglutethimide: selective inhibition of cholesterol side-chain cleavage Allan B. Foster, Michael Jarman, Chui Sheung Leung, Martin G. Rowlands, and Grahame N. Taylor pp 50 - 54; DOI: 10.1021/jm00355a011 |
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Synthesis of exo-3-phenylbicyclo[3.2.1]oct-3-en-2-amine and related compounds as potential analgesics Alan Harris, David Middlemiss, Keith Mills, Alma J. Gower, and Michael B. Tyers pp 55 - 60; DOI: 10.1021/jm00355a012 |
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New carboxyalkyl inhibitors of brain enkephalinase: synthesis, biological activity and analgesic properties Marie Claude Fournie-Zaluski, Pierre Chaillet, Evelyne Soroca-Lucas, Helene Marcais-Collado, Jean Costentin, and Bernard P. Roques pp 60 - 65; DOI: 10.1021/jm00355a013 |
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Stereochemical aspects of conjugation reactions catalyzed by rat liver glutathione S-transferase isozymes James B. Mangold and Mahmoud M. Abdel-Monem pp 66 - 71; DOI: 10.1021/jm00355a014 |
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Synthesis and 5-lipoxygenase inhibitory activities of eicosanoid compounds Yoshinobu Arai, Katsuichi Shimoji, Mitoshi Konno, Yoshitaka Konishi, Shigehiro Okuyama, Sadahiko Iguchi, Masaki Hayashi, Tsumoru Miyamoto, and Masaaki Toda pp 72 - 78; DOI: 10.1021/jm00355a015 |
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Novel 17.alpha.-chloro-17.beta.-sulfoxide steroids as specific inhibitors of sebaceous gland activity: potential antiacne agents Michael J. Green, Robert Tiberi, Richard W. Draper, F. Emilie Carlon, Rudolph O. Neri, Ted T. Kung, Andrew T. McPhail, and Kay D. Onan pp 78 - 85; DOI: 10.1021/jm00355a016 |
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Acute effects of alkylating agents on canine renal function: specifically designed synthetic maleimides Daniel A. Koechel, Joan B. Tarloff, and Gary O. Rankin pp 85 - 90; DOI: 10.1021/jm00355a017 |
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1,2-Dihydropyrido[3,4-b]pyrazines: structure-activity relationships Carroll Temple, Glynn P. Wheeler, Robert D. Elliott, Jerry D. Rose, Robert N. Comber, and John A. Montgomery pp 91 - 95; DOI: 10.1021/jm00355a018 |
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Anticoccidial derivatives of 6-azauracil. 5. Potentiation by benzophenone side chains Ronnie D. Carroll, Max W. Miller, Banavara L. Mylari, Larry R. Chappel, Harold L. Howes, Martin J. Lynch, John E. Lynch, Shyam K. Gupta, Jay J. Rash, and Richard C. Koch pp 96 - 100; DOI: 10.1021/jm00355a019 |
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2-Benzazepines. 2. Thiazolo[5,4-d][2]benzazepines Louis E. Benjamin, R. Ian Fryer, Norman W. Gilman, and Eugene J. Trybulski pp 100 - 103; DOI: 10.1021/jm00355a020 |
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Synthesis and biological activity of a 2-bromoethylamine (mustard) derivative of hemicholinium-3 and hemicholinium-15 Louis A. Smart pp 104 - 107; DOI: 10.1021/jm00355a021 |
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Synthesis and antiallergy activity of 5-oxo-5H-thiazolo[2,3-b]quinazolinecarboxylic acids Ronald A. LeMahieu, Mathew Carson, Ann F. Welton, Herman W. Baruth, and Bohdan Yaremko pp 107 - 110; DOI: 10.1021/jm00355a022 |
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Synthesis and characterization of a fluorescent analog of methotrexate A. Ashok Kumar, James H. Freisheim, Robert J. Kempton, Gregory M. Anstead, Angelique M. Black, and Larry Judge pp 111 - 113; DOI: 10.1021/jm00355a023 |
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2-(Hydroxyphenyl)indoles: a new class of mammary tumor-inhibiting compounds Erwin Von Angerer and Jelica Prekajac pp 113 - 116; DOI: 10.1021/jm00355a024 |
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Book Reviews pp 117 - 120; DOI: 10.1021/jm00355a600 |
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Radioiodine-labeled N,N-dimethyl-N'-[2-hydroxy-3-alkyl-5-iodobenzyl]-1,3-propanediamines for brain perfusion imaging Kenneth M. Tramposch, Hank F. Kung, and Monte Blau pp 121 - 125; DOI: 10.1021/jm00356a001 |
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Structure-activity studies of highly potent cyclic [Cys4, Cys10]melanotropin analogs James J. Knittel, Tomi K. Sawyer, Victor J. Hruby, and Mac E. Hadley pp 125 - 129; DOI: 10.1021/jm00356a002 |
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Synthesis of partially modified retro-inverso substance P analogs and their biological activity Michael Chorev, Elie Rubini, Chaim Gilon, Uri Wormser, and Zvi Selinger pp 129 - 135; DOI: 10.1021/jm00356a003 |
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Folate analogs. 20. Synthesis and antifolate activity of 1',2',3',4',5',6'-hexahydrohomofolic acid M. G. Nair, Eldridge B. Otis, Roy L. Kisliuk, and Y. Gaumont pp 135 - 140; DOI: 10.1021/jm00356a004 |
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Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogs related to cimetidine and tiotidine Jacob M. Hoffman, Adolph M. Pietruszkiewicz, Charles N. Habecker, Brian T. Phillips, William A. Bolhofer, Edward J. Cragoe, Mary Lou Torchiana, William C. Lumma, and John J. Baldwin pp 140 - 144; DOI: 10.1021/jm00356a005 |
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In vitro and in vivo protection of acetylcholinesterase against organophosphate poisoning by pretreatment with a novel derivative of 1,3,2-dioxaphosphorinane 2-oxide Y. Ashani, H. Leader, L. Raveh, R. Bruckstein, and M. Spiegelstein pp 145 - 152; DOI: 10.1021/jm00356a006 |
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Nucleosides. 123. Synthesis of antiviral nucleosides: 5-substituted 1-(2-deoxy-2-halogeno-.beta.-D-arabinofuranosyl)cytosines and -uracils. Some structure-activity relationships Kyoichi A. Watanabe, Tsann Long Su, Robert S. Klein, Chung K. Chu, Akira Matsuda, Moon Woo Chun, Carlos Lopez, and Jack J. Fox pp 152 - 156; DOI: 10.1021/jm00356a007 |
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Carbocyclic analogs of 5-substituted uracil nucleosides. Synthesis and antiviral activity Y. Fulmer Shealy, C. Allen O'Dell, William M. Shannon, and Gussie Arnett pp 156 - 161; DOI: 10.1021/jm00356a008 |
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Some adenine and adenosine methylene-bridged estrogens Vaidyanathan K. Iyer, W. Barkley Butler, Jerome P. Horwitz, Jurij Rozhin, Sam C. Brooks, Jeanne Corombos, and David Kessel pp 162 - 166; DOI: 10.1021/jm00356a009 |
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Analogs of 2'(3')-O-L-phenylalanyladenosine as substrates and inhibitors of ribosomal peptidyltransferase Jiri Zemlicka, Aruna Bhuta, and Prakash Bhuta pp 167 - 174; DOI: 10.1021/jm00356a010 |
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1-(4-Aminobenzyl)- and 1-(4-aminophenyl)isoquinoline derivatives: synthesis and evaluation as potential irreversible cyclic nucleotide phosphodiesterase inhibitors Kathleen A. Walker, Marvin R. Boots, James F. Stubbins, Michael E. Rogers, and Craig W. Davis pp 174 - 181; DOI: 10.1021/jm00356a011 |
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Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications Christian Rivalle, Francoise Wendling, Pierre Tambourin, Jean Marc Lhoste, Emile Bisagni, and Jean Claude Chermann pp 181 - 185; DOI: 10.1021/jm00356a012 |
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Synthesis and antileishmanial activity of 6-methoxy-4-methyl-N-[6-(substituted-1-piperazinyl)hexyl]-8-quinolinamines and related compounds Judith L. Johnson and Leslie M. Werbel pp 185 - 194; DOI: 10.1021/jm00356a013 |
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Buspirone analogs. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives J. P. Yevich, D. L. Temple, J. S. New, Duncan P. Taylor, and L. A. Riblet pp 194 - 203; DOI: 10.1021/jm00356a014 |
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Theoretical conformational studies of some dopamine antagonistic benzamide drugs: 3-pyrrolidyl- and 4-piperidyl derivatives Han Van de Waterbeemd and Bernard Testa pp 203 - 207; DOI: 10.1021/jm00356a015 |
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Synthesis and antihypertensive activity of stereoisomers of 4-piperidyl-1,3-dihydro-2-oxo-2H-benzimidazoles. Enhanced potencies of (+)-isomers Yutaka Kasuya, Koki Shigenobu, Makiko Hashikami, Naoko Karashima, Hiroyuki Obase, Haruki Takai, Masayuki Teranishi, Akira Karasawa, and Kazuhiro Kubo pp 208 - 213; DOI: 10.1021/jm00356a016 |
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New antihypertensive cannabinoids Harold E. Zaugg and Jaroslav Kyncl pp 214 - 217; DOI: 10.1021/jm00356a017 |
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2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents Fortuna Haviv, Robert W. DeNet, Raymond J. Michaels, James D. Ratajczyk, George W. Carter, and Patrick R. Young pp 218 - 222; DOI: 10.1021/jm00356a018 |
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Nonsteroidal antiinflammatory agents. 2. [(Heteroarylamino)phenyl]alkanoic acids Katsuhiko Hino, Hideo Nakamura, Yasutaka Nagai, Hitoshi Uno, and Haruki Nishimura pp 222 - 226; DOI: 10.1021/jm00356a019 |
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Replacement of aromatic or heteroaromatic groups in nonsteroidal antiinflammatory agents with the ferrocene group Bruce E. Maryanoff, Stanley L. Keeley, and Frank J. Persico pp 226 - 229; DOI: 10.1021/jm00356a020 |
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Cardiac-slowing amidines containing the 3-thioindole group. Potential antianginal agents Michael J. Zelesko, David F. McComsey, William E. Hageman, Samuel O. Nortey, Carol A. Baker, and Bruce E. Maryanoff pp 230 - 237; DOI: 10.1021/jm00356a021 |
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Hypolipidemic activity of phthalimide derivatives. 2. N-Phenylphthalimide and derivatives James M. Chapman, P. Josee Voorstad, George H. Cocolas, and Iris H. Hall pp 237 - 243; DOI: 10.1021/jm00356a022 |
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Hypolipidemic activity of phthalimide derivatives. 3. A comparison of phthalimide and 1,2-benzisothiazolin-3-one 1,1-dioxide derivatives to phthalimidine and 1,2-benzisothiazoline 1,1-dioxide congeners James M. Chapman, George H. Cocolas, and Iris H. Hall pp 243 - 246; DOI: 10.1021/jm00356a023 |
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Synthesis and antianxiety activity of (.omega.-piperazinylalkoxy)indan derivatives Ryoji Kikumoto, Akihiro Tobe, Harukazu Fukami, and Mitsuo Egawa pp 246 - 250; DOI: 10.1021/jm00356a024 |
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Studies on v-triazoles. 7. Antiallergic 9-oxo-1H,9H-benzopyrano[2,3-d]-v-triazoles Derek R. Buckle, D. James Outred, Caroline J. M. Rockell, Harry Smith, and Barbara A. Spicer pp 251 - 254; DOI: 10.1021/jm00356a025 |
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Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogs E. Epifani, A. Lapucci, B. Macchia, F. Macchia, P. Tognetti, M. C. Breschi, M. Del Tacca, E. Martinotti, and L. Giovannini pp 254 - 259; DOI: 10.1021/jm00356a026 |
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.beta.-Lactam antibiotics: geometrical requirements for antibacterial activities N. Claude Cohen pp 259 - 264; DOI: 10.1021/jm00356a027 |
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Synthesis of esters of phosphonoformic acid and their antiherpes activity Jan O. Noren, Erik Helgstrand, Nils G. Johansson, Alfons Misiorny, and Goeran Stening pp 264 - 270; DOI: 10.1021/jm00356a028 |
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Synthesis and biological activities of the (Z) isomers of carbapenem antibiotics Setsuo Harada, Shigetoshi Tsubotani, Mitsuko Asai, Kenji Okonogi, and Masahiro Kondo pp 271 - 275; DOI: 10.1021/jm00356a029 |
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Selection of test series by a modified multidimensional mapping method Raymond Wootton pp 275 - 277; DOI: 10.1021/jm00356a030 |
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New azacannabinoids highly active in the central nervous system Cheuk Man Lee, Harold E. Zaugg, Raymond J. Michaels, Anthony T. Dren, Nicholas P. Plotnikoff, and Patrick R. Young pp 278 - 280; DOI: 10.1021/jm00356a031 |
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2'-O-Nitro-1-.beta.-D-arabinofuranosylcytosine. A new derivative of 1-.beta.-D-arabinofuranosylcytosine that resists enzymic deamination and has antileukemic activity T. Ling Chwang, Arnold Fridland, and Thomas L. Avery pp 280 - 283; DOI: 10.1021/jm00356a032 |
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Synthesis of an N-aminopyrazinonium analog of cytidine Tzoong Chyh Lee, Paul L. Chello, Ting Chao Chou, Mary Agnes Templeton, and James C. Parham pp 283 - 286; DOI: 10.1021/jm00356a033 |
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Syntheses and antitumor activity of 2-deoxyribofuranosides of 3-deazaguanine A. Mohsin Mian and Tasneem A. Khwaja pp 286 - 291; DOI: 10.1021/jm00356a034 |
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A synthetic approach to poly(.gamma.-glutamyl) conjugates of methotrexate James R. Piper, George S. McCaleb, and John A. Montgomery pp 291 - 294; DOI: 10.1021/jm00356a035 |
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Aromatic amidines. Comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin R. R. Tidwell, J. D. Geratz, and E. J. Dubovi pp 294 - 298; DOI: 10.1021/jm00356a036 |
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Syntheses of iron(II) bis(pyridoxal isonicotinoylhydrazone)s and the in vivo iron-removal properties of some pyridoxal derivatives S. Avramovici-Grisaru, S. Sarel, G. Link, and C. Hershko pp 298 - 302; DOI: 10.1021/jm00356a037 |
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Synthesis and carcinogenic activity of oxidized benzacridines: potential metabolites of the strong carcinogen 7-methylbenz[c]acridine and of the inactive isomer 12-methylbenz[a]acridine Martine Croisy-Delcey, Alain Croisy, Francois Zajdela, and Jean Marc Lhoste pp 303 - 306; DOI: 10.1021/jm00356a038 |
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Book Reviews pp 306 - 308; DOI: 10.1021/jm00356a600 |
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Mutagenicity and chemistry of N-nitroso-N-(parasubstituted-benzyl)methylamines George M. Singer and A. W. Andrews pp 309 - 312; DOI: 10.1021/jm00357a001 |
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Improved delivery through biological membranes. 11. A redox chemical drug-delivery system and its use for brain-specific delivery of phenylethylamine Nicholas Bodor and Hassan H. Farag pp 313 - 318; DOI: 10.1021/jm00357a002 |
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Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach Nicholas Bodor, Alan J. Harget, and Edward W. Phillips pp 318 - 328; DOI: 10.1021/jm00357a003 |
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Structure-activity studies of configurationally rigid arylprostaglandins Thomas K. Schaaf, M. Ross Johnson, Jay W. Constantine, Jasjit S. Bindra, Hans Juergen Hess, and Walter Elger pp 328 - 334; DOI: 10.1021/jm00357a004 |
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11,12-Secoprostaglandins. 6. Interphenylene analogs of acylhydroxyalkanoic acids and related compounds as renal vasodilators John B. Bicking, Charles M. Robb, Edward J. Cragoe, Edward H. Blaine, L. Sherman Watson, and Mary C. Dunlay pp 335 - 341; DOI: 10.1021/jm00357a005 |
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Prostaglandin isosteres. 2. Chain-modified thiazolidinone prostaglandin analogs as renal vasodilators John B. Bicking, Mark G. Bock, Edward J. Cragoe Jr., Robert M. DiPardo, Norman Gould P, Wilbur J. Holtz, T. J. Lee, Charles M. Robb, Robert L. Smith, and et al. pp 342 - 348; DOI: 10.1021/jm00357a006 |
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Synthesis and evaluation of 1- and 2-substituted fentanyl analogs for opioid activity Mohamed Y. H. Essawi and Philip S. Portoghese pp 348 - 352; DOI: 10.1021/jm00357a007 |
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.beta.-Adrenergic blocking agents. 23. 1-(Substituted-amido)phenoxy-3-[[(substituted-amido)alkyl]amino]propan-2-ols M. S. Large and L. H. Smith pp 352 - 357; DOI: 10.1021/jm00357a008 |
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Piperazinylimidazo[1,2-a]pyrazines with selective affinity for in vitro .alpha.-adrenergic receptor subtypes William C. Lumma, William C. Randall, E. L. Cresson, Joel R. Huff, Richard D. Hartman, and T. F. Lyon pp 357 - 363; DOI: 10.1021/jm00357a009 |
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Synthesis of (7R)-7H-indolo[3,4-gh][1,4]benzoxazines, a new class of D-heteroergolines with dopamine agonist activity Paul S. Anderson, John J. Baldwin, David E. McClure, George F. Lundell, James H. Jones, William C. Randall, Gregory E. Martin, Michael Williams, Jordan M. Hirshfield, and et al. pp 363 - 367; DOI: 10.1021/jm00357a010 |
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2-Benzazepines. [1,2,3]Triazolo[4,5-d][2]benzazepines and dibenzo[c,f][1,2,3]triazolo[3,4-a]azepines. Synthesis and evaluation as central nervous system agents E. J. Trybulski, L. Benjamin, S. Vitone, A. Walser, and R. I. Fryer pp 367 - 372; DOI: 10.1021/jm00357a011 |
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Pyridazinones. 2. Synthesis and antisecretory and antiulcer activities of thiourea and 2-cyanoguanidine derivatives Toshihiro Yamada, Youichi Nobuhara, Hiroshi Shimamura, Yoshitsugu Tsukamoto, Kazuo Yoshihara, Azuma Yamaguchi, and Masahiko Ohki pp 373 - 381; DOI: 10.1021/jm00357a012 |
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Antihypertensive agents: angiotensin converting enzyme inhibitors. 1-[3-(Acylthio)-3-aroylpropionyl]-L-prolines Francis J. McEvoy, Fong M. Lai, and J. Donald Albright pp 381 - 393; DOI: 10.1021/jm00357a013 |
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(Mercaptopropanoyl)indoline-2-carboxylic acids and related compounds as potent angiotensin converting enzyme inhibitors and antihypertensive agents Dong H. Kim, Charles J. Guinosso, George C. Buzby, David R. Herbst, Ronald J. McCaully, Thomas C. Wicks, and Robert L. Wendt pp 394 - 403; DOI: 10.1021/jm00357a014 |
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Antihypertensive activity of 6-arylpyrido[2,3-d]pyrimidin-7-amine derivatives. 2. 7-Acyl amide analogs C. John Blankley, Lawrence R. Bennett, Robert W. Fleming, Ronald D. Smith, Deirdre K. Tessman, and Harvey R. Kaplan pp 403 - 411; DOI: 10.1021/jm00357a015 |
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Pyrimidine derivatives. 4. Synthesis and antihypertensive activity of 4-amino-2-(4-cinnamoylpiperazino)-6,7-dimethoxyquinazoline derivatives Tetsuo Sekiya, Hidetoshi Hiranuma, Shunsuke Hata, Susumu Mizogami, Mitsuo Hanazuka, and Shunichi Yamada pp 411 - 416; DOI: 10.1021/jm00357a016 |
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Synthesis and antihypertensive activity of 2-sulfonamido- and 2-sulfamido-1,3,4,6,7,11b.alpha.-hexahydro-2H-benzo[a]quinolizines John L. Archibald, David R. Beardsley, Terence J. Ward, John F. Waterfall, and John F. White pp 416 - 420; DOI: 10.1021/jm00357a017 |
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(E)-3-(4-oxo-4H-quinazolin-3-yl)-2-propenoic acids, a new series of antiallergy agents Ronald A. LeMahieu, Mathew Carson, William C. Nason, David R. Parrish, Ann F. Welton, Herman W. Baruth, and Bohdan Yaremko pp 420 - 425; DOI: 10.1021/jm00357a018 |
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Synthesis and biological activity of zoapatanol analogs Mansukh C. Wani, B. Rao Vishnuvajjala, William E. Swain, Douglas H. Rector, Clarence E. Cook, Vladimir Petrow, Jerry R. Reel, Kathleen M. Allen, and Samuel G. Levine pp 426 - 430; DOI: 10.1021/jm00357a019 |
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Mannich bases of 4-phenyl-3-buten-2-one. A new class of antiherpes agent M. L. Edwards, H. W. Ritter, D. M. Stemerick, and K. T. Stewart pp 431 - 436; DOI: 10.1021/jm00357a020 |
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Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives K. Seamon, J. W. Daly, H. Metzger, N. J. De Souza, and J. Reden pp 436 - 439; DOI: 10.1021/jm00357a021 |
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Ferric ion sequestering agents. 11. Synthesis and kinetics of iron removal from transferrin of catechoyl derivatives of desferrioxamine B Steven J. Rodgers and Kenneth N. Raymond pp 439 - 442; DOI: 10.1021/jm00357a022 |
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Synthesis of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride, a novel, orally active antifungal agent R. L. Dyer, G. J. Ellames, B. J. Hamill, P. W. Manley, and A. M. S. Pope pp 442 - 445; DOI: 10.1021/jm00357a023 |
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Synthesis and antitumor activity of 2-.beta.-D-ribofuranosylselenazole-4-carboxamide and related derivatives Prem C. Srivastava and Roland K. Robins pp 445 - 448; DOI: 10.1021/jm00357a024 |
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DNA binding studies of 7-bulky substituted actinomycin analogs Thomas F. Brennan and Sisir K. Sengupta pp 448 - 451; DOI: 10.1021/jm00357a025 |
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Synthesis and antiarrhythmic activity of new [(dialkylamino)alkyl]pyridylacetamides Claude A. Bernhart, Christian Condamine, Henri Demarne, Romeo Roncucci, Jean Pierre Gagnol, Patrick J. Gautier, and Martine A. Serre pp 451 - 455; DOI: 10.1021/jm00357a026 |
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Derivatives of .beta.-adrenergic antagonists: N-nitrosopropranolol and N-hydroxypropranolol and its aldonitrone Shoufang Zhang, Mark L. Powell, Wendel L. Nelson, and Peter J. Wirth pp 455 - 458; DOI: 10.1021/jm00357a027 |
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Book Reviews pp 458 - 462; DOI: 10.1021/jm00357a600 |
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Mechanism of steroid anesthetic action: interactions of alphaxalone and .DELTA.16-alphaxalone with bilayer vesicles Alexandros Makriyannis and Stephen Fesik pp 463 - 465; DOI: 10.1021/jm00358a001 |
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Modified steroid hormones. 7. 4-Fluoro-17.beta.-estradiol:carbon-13 nuclear magnetic resonance, crystal and molecular structure, and biological activity Moshe Neeman, Gopinath Kartha, Kuantee Go, Joseph P. Santodonato, and Onda Dodson-Simmons pp 465 - 469; DOI: 10.1021/jm00358a002 |
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Structure-activity relationships of synthetic antibiotic analogs of anisomycin Stan S. Hall, David Loebenberg, and Doris P. Schumacher pp 469 - 475; DOI: 10.1021/jm00358a003 |
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Quantitative structure-activity relationships for 2-[(phenylmethyl)sulfonyl]pyridine 1-oxide herbicides Arthur M. Doweyko, Allyn R. Bell, John A. Minatelli, and Douglas I. Relyea pp 475 - 478; DOI: 10.1021/jm00358a004 |
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Geometries and conformational processes in phencyclidine and a rigid adamantyl analog: variable-temperature NMR, x-ray crystallographic, and molecular mechanics studies Thomas A. Eaton, K. N. Houk, Steven F. Watkins, and Frank R. Fronczek pp 479 - 486; DOI: 10.1021/jm00358a005 |
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The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity Sujata V. Bhat, Alihussein N. Dohadwalla, Balbir S. Bajwa, Nandkumar K. Dadkar, Horst Dornauer, and Noel J. De Souza pp 486 - 492; DOI: 10.1021/jm00358a006 |
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Conjugates of catecholamines. 1. N-Alkyl-functionalized carboxylic acid congeners and amides related to isoproterenol Kenneth A. Jacobson, Debra Marr-Leisy, Roberto P. Rosenkranz, Michael S. Verlander, Kenneth L. Melmon, and Murray Goodman pp 492 - 499; DOI: 10.1021/jm00358a007 |
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.beta.-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of .beta.-carboline-3-carboxylic acid Klaus P. Lippke, Walter G. Schunack, Wolfgang Wenning, and Walter E. Mueller pp 499 - 503; DOI: 10.1021/jm00358a008 |
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Alkylation of opioid receptor subtypes by .alpha.-chlornaltrexamine produces concurrent irreversible agonistic and irreversible antagonistic activities L. M. Sayre, A. E. Takemori, and P. S. Portoghese pp 503 - 506; DOI: 10.1021/jm00358a009 |
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Synthesis of 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinolines and their actions at adrenoceptors in vivo and in vitro David Beaumont, Roger D. Waigh, Methi Sunbhanich, and Michael W. Nott pp 507 - 515; DOI: 10.1021/jm00358a010 |
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Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors John L. Neumeyer, Dirk Reischig, George W. Arana, Alexander Campbell, Ross J. Baldessarini, Nora S. Kula, and Keith J. Watling pp 516 - 521; DOI: 10.1021/jm00358a011 |
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Synthesis and central dopaminergic activities of (.+-.)-hexahydro-4H-indolo[3,4-gh][1,4]benzoxazine derivatives [(.+-.)-9-oxaergolines] Lucien Nedelec, Andre Pierdet, Patrick Fauveau, Catherine Euvrard, Claude Dumont, Jacques R. Boissier, Fernand Labrie, and Louise Proulx-Ferland pp 522 - 527; DOI: 10.1021/jm00358a012 |
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Improved delivery through biological membranes. 13. Brain-specific delivery of dopamine with a dihydropyridine .dblharw. pyridinium salt type redox delivery system Nicholas Bodor and Hassan H. Farag pp 528 - 534; DOI: 10.1021/jm00358a013 |
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4-(Diphenylmethyl)-1-(iminomethyl)piperidines as gastric antisecretory agents Malcolm K. Scott, Henry I. Jacoby, John E. Mills, Antoinette C. Bonfilio, and C. Royce Rasmussen pp 535 - 538; DOI: 10.1021/jm00358a014 |
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Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives William A. Bolhofer, Albert A. Deana, Charles N. Habecker, Jacob M. Hoffman, Norman P. Gould, Adolph M. Pietruszkiewicz, John D. Prugh, Mary Lou Torchiana, Edward J. Cragoe, and Ralph Hirschmann pp 538 - 544; DOI: 10.1021/jm00358a015 |
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Synthesis and antineoplastic activity of 3'-azido and 3'-amino analogs of pyrimidine deoxyribonucleoside Tai Shun Lin and William R. Mancini pp 544 - 548; DOI: 10.1021/jm00358a016 |
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Design, synthesis, and testing of antisickling agents. 2. Proline derivatives designed for the donor site D. J. Abraham, M. Mokotoff, L. Sheh, and J. E. Simmons pp 549 - 554; DOI: 10.1021/jm00358a017 |
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Synthesis and some pharmacological properties of oxytocin and vasopressin analogs with sarcosine or N-methyl-L-alanine in position 7 Zbigniew Grzonka, Bernard Lammek, Franciszek Kasprzykowski, Diana Gazis, and Irving L. Schwartz pp 555 - 559; DOI: 10.1021/jm00358a018 |
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Preparation of 2-amino-4(3H)-oxopyrimido[5,4-b][1,4]thiazines (5-thiapterins) and their evaluation as cofactors for phenylalanine hydroxylase Robert N. Henrie, Robert A. Lazarus, and Stephen J. Benkovic pp 559 - 563; DOI: 10.1021/jm00358a019 |
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Preparation of some 10-[3-(dimethylamino)propyl]-10H-pyrazino[2,3-b][1,4]benzothiazines as potential neuroleptics Walfred S. Saari, David W. Cochran, Yung C. Lee, Emlen L. Cresson, James P. Springer, Michael Williams, James A. Totaro, and George G. Yarbrough pp 564 - 569; DOI: 10.1021/jm00358a020 |
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Substituted 1,4-naphthoquinones vs. the ascitic sarcoma 180 of mice Ernest M. Hodnett, Chinda Wongwiechintana, William J. Dunn, and Pam Marrs pp 570 - 574; DOI: 10.1021/jm00358a021 |
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o-Quinone formation in the biochemical oxidation of the antitumor drug N2-methyl-9-hydroxyellipticinium acetate Jean Bernadou, Gerard Meunier, Claude Paoletti, and Bernard Meunier pp 574 - 579; DOI: 10.1021/jm00358a022 |
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2-(Aminomethyl)phenols, a new class of saluretic agents. 5. Fused-ring analogs A. A. Deana, G. E. Stokker, E. M. Schultz, R. L. Smith, E. J. Cragoe, H. F. Russo, and L. S. Watson pp 580 - 585; DOI: 10.1021/jm00358a023 |
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2-(Aminomethyl)phenols, a new class of saluretic agents. 6. Effects of N,O-spiroannulation and subsequent quarternization G. E. Stokker, E. M. Schultz, R. L. Smith, E. J. Cragoe, H. F. Russo, L. S. Watson, C. T. Ludden, and C. S. Sweet pp 585 - 590; DOI: 10.1021/jm00358a024 |
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Anticoccidial activity of crown polyethers George R. Brown and Alan J. Foubister pp 590 - 592; DOI: 10.1021/jm00358a025 |
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Antifertility agents. 38. Effect of the side chain and its position on the activity of 3,4-diarylchromans M. Salman, Suprabhat Ray, A. K. Agarwal, S. Durani, B. S. Setty, V. P. Kamboj, and N. Anand pp 592 - 595; DOI: 10.1021/jm00358a026 |
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Phosphonate analogs of pyridoxal phosphate with shortened side chains Chi Neng A. Han, Chuzo Iwata, and David E. Metzler pp 595 - 598; DOI: 10.1021/jm00358a027 |
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Synthesis and biological activity of 5-(trifluoromethyl)- and 5-(pentafluoroethyl)pyrimidine nucleoside analogs Tai Shun Lin and You Song Gao pp 598 - 601; DOI: 10.1021/jm00358a028 |
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Synthesis and antiviral activity of water-soluble esters of acyclovir [9-[(2-hydroxyethoxy)methyl]guanine) Leon Colla, Erik De Clercq, Roger Busson, and Hubert Vanderhaeghe pp 602 - 604; DOI: 10.1021/jm00358a029 |
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Folate analogs. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid M. G. Nair, David C. Salter, R. L. Kisliuk, Y. Gaumont, G. North, and F. M. Sirotnak pp 605 - 607; DOI: 10.1021/jm00358a030 |
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Synthesis and antiallergic activity of some acidic derivatives of 4H-pyrimido[2,1-b]benzazol-4-ones James J. Wade, Cristeta B. Toso, Charles J. Matson, and Vincent L. Stelzer pp 608 - 611; DOI: 10.1021/jm00358a031 |
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Antimycotic azoles. 6. Synthesis and antifungal properties of terconazole, a novel triazole ketal J. Heeres, R. Hendrickx, and J. Van Cutsem pp 611 - 613; DOI: 10.1021/jm00358a032 |
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Book Reviews pp 614 - 618; DOI: 10.1021/jm00358a600 |
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Anxioselective anxiolytics Michael Williams pp 619 - 628; DOI: 10.1021/jm00359a001 |
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Synthesis of N-(substituted phenyl)-D-xylopyranosylamines as potential modifiers of the formation of glycosaminoglycans Lin Wang, Charles A. Maniglia, Sharon L. Mella, and Alan C. Sartorelli pp 629 - 632; DOI: 10.1021/jm00359a002 |
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Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard Prasun K. Chakravarty, Philip L. Carl, Michael J. Weber, and John A. Katzenellenbogen pp 633 - 638; DOI: 10.1021/jm00359a003 |
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Plasmin-activated prodrugs for cancer chemotherapy. 2. Synthesis and biological activity of peptidyl derivatives of doxorubicin Prasun K. Chakravarty, Philip L. Carl, Michael J. Weber, and John A. Katzenellenbogen pp 638 - 644; DOI: 10.1021/jm00359a004 |
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Cardioselectivity of .beta.-adrenoceptor blocking agents. 2. Role of the amino group substituent W. J. Rzeszotarski, R. E. Gibson, D. A. Simms, E. M. Jagoda, J. N. Vaughan, and W. C. Eckelman pp 644 - 648; DOI: 10.1021/jm00359a005 |
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Antihypertensive .beta.-adrenergic blocking agents: N-aralkyl analogs of 2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine David E. McClure, John J. Baldwin, William C. Randall, Thomas F. Lyon, K. Mensler, G. F. Lundell, A. W. Raab, Dennis Gross, Edwin A. Risley, and et al. pp 649 - 657; DOI: 10.1021/jm00359a006 |
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Synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones Robin D. Clark, Joan M. Caroon, Arthur F. Kluge, David B. Repke, Adolph P. Roszkowski, Arthur M. Strosberg, Stephen Baker, Susan M. Bitter, and Marlys D. Okada pp 657 - 661; DOI: 10.1021/jm00359a007 |
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Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides Erik De Clercq, Johan Descamps, Jan Balzarini, Jerzy Giziewicz, Philip J. Barr, and Morris J. Robins pp 661 - 666; DOI: 10.1021/jm00359a008 |
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2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 6. A one-step synthesis of new trimethoprim derivatives and activity analysis by molecular modeling Alexander Stuart, Thomas Paterson, Barbara Roth, and Edward Aig pp 667 - 673; DOI: 10.1021/jm00359a009 |
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Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine K. Misiura, A. Okruszek, K. Pankiewicz, W. J. Stec, Z. Czownicki, and B. Utracka pp 674 - 679; DOI: 10.1021/jm00359a010 |
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Activated cyclophosphamide anticancer drugs: molecular structures of cis- and trans-4-hydroperoxyisophosphamides Arthur Camerman, H. Warren Smith, and Norman Camerman pp 679 - 683; DOI: 10.1021/jm00359a011 |
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Structures of two isomeric bicyclic derivatives of 4-hydroperoxyisophosphamide Norman Camerman, J. Keith Fawcett, and Arthur Camerman pp 683 - 686; DOI: 10.1021/jm00359a012 |
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Quantitative structure-activity relationship of double alkyl chain drugs Sakae Hada, Saburo Neya, and Noriaki Funasaki pp 686 - 693; DOI: 10.1021/jm00359a013 |
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Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study Jacques Gilbert, Jean Francois Miquel, Gilles Precigoux, Michel Hospital, Jean Pierre Raynaud, Francoise Michel, and Andre Crastes de Paulet pp 693 - 699; DOI: 10.1021/jm00359a014 |
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Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives C. S. Rooney, W. C. Randall, K. B. Streeter, C. Ziegler, E. J. Cragoe Jr., H. Schwam, S. R. Michelson, H. W. R. Williams, E. Eichler, and et al. pp 700 - 714; DOI: 10.1021/jm00359a015 |
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Studies on v-triazoles. 9. Antiallergic 4,9-dihydro-4,9-dioxo-1H-naphtho[2,3-d]-v-triazoles Derek R. Buckle, Harry Smith, Barbara A. Spicer, and John Martin Tedder pp 714 - 719; DOI: 10.1021/jm00359a016 |
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Structure-activity correlations for a series of antiallergy agents. 2. Geometric and electronic characterization of some oxamic and dioxamic acids B. Vernon Cheney, David J. Duchamp, and Ralph E. Christoffersen pp 719 - 725; DOI: 10.1021/jm00359a017 |
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Structure-activity correlations for a series of antiallergy agents. 3. Development of quantitative model B. Vernon Cheney and Ralph E. Christoffersen pp 726 - 737; DOI: 10.1021/jm00359a018 |
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Synthesis and biological distribution of radiolabeled ammineruthenium(III)-amino acid complexes as potential pancreatic imaging agents Carol D. Meyer, Michael A. Davis, and Cecily J. Periana pp 737 - 742; DOI: 10.1021/jm00359a019 |
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Potential cerebral perfusion agents: synthesis and evaluation of a radioiodinated vinylalkylbarbituric acid analog Prem C. Srivastava, Alvin P. Callahan, Evelyn B. Cunningham, and Furn F. Knapp pp 742 - 746; DOI: 10.1021/jm00359a020 |
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Sulfur analogs of psychotomimetic agents. 2. Analogs of (2,5-dimethoxy-4-methylphenyl)- and of (2,5-dimethoxy-4-ethylphenyl)isopropylamine Peyton Jacob and Alexander T. Shulgin pp 746 - 752; DOI: 10.1021/jm00359a021 |
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Oscillations in some linear free energy relationships derived from partition coefficients of phenols between octanol and water A. E. Beezer and W. H. Hunter pp 757 - 759; DOI: 10.1021/jm00359a022 |
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9-(1,3-Dihydroxy-2-propoxymethyl)guanine: a new potent and selective antiherpes agent John C. Martin, Charles A. Dvorak, Donald F. Smee, Thomas R. Matthews, and Julien P. H. Verheyden pp 759 - 761; DOI: 10.1021/jm00359a023 |
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Synthesis and analgesic properties of two leucine-enkephalin analogs containing a conformationally restrained N-terminal tyrosine residue Trevor Deeks, Peter A. Crooks, and Roger D. Waigh pp 762 - 765; DOI: 10.1021/jm00359a024 |
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Antidepressant activity of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols William J. Houlihan, John H. Gogerty, Vincent A. Parrino, and Eileen Ryan pp 765 - 768; DOI: 10.1021/jm00359a025 |
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1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]vinyl]-1H-imidazole hydrochloride, a new potent antifungal agent Masaru Ogata, Hiroshi Matsumoto, Yoshinori Hamada, Mitsunori Takehara, and Katsuya Tawara pp 768 - 770; DOI: 10.1021/jm00359a026 |
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Synthesis and Biological Activities of the Z Isomers of Carbapenem Antibiotics Setsuo Harada, Shigetoshi Tsubotani, Mitsuko Asai, Kenji Okonogi, and Masahiro Kondo pp 753 - 757; DOI: 10.1021/jm00359a600 |
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Book Reviews pp 771 - 774; DOI: 10.1021/jm00359a601 |
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New developments in calcium ion channel antagonists R. A. Janis and D. J. Triggle pp 775 - 785; DOI: 10.1021/jm00360a001 |
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Synthesis and gastric antisecretory properties of 4,5 unsaturated derivatives of 15-deoxy-16-hydroxy-16-methylprostaglandin E1 Paul W. Collins, Esam Z. Dajani, Raphael Pappo, Alan F. Gasiecki, Robert G. Bianchi, and Emmett M. Woods pp 786 - 790; DOI: 10.1021/jm00360a002 |
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Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogs Gordon L. Bundy, D. R. Morton, D. C. Peterson, E. E. Nishizawa, and W. L. Miller pp 790 - 799; DOI: 10.1021/jm00360a003 |
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6-Aryl-4,5-dihydro-3(2H)-pyridazinones. A new class of compounds with platelet aggregation inhibiting and hypotensive activities M. Thyes, H. D. Lehmann, J. Gries, H. Koenig, R. Kretzschmar, J. Kunze, R. Lebkuecher, and D. Lenke pp 800 - 807; DOI: 10.1021/jm00360a004 |
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Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 1. Heteroarylamine derivatives David M. Stout, W. L. Matier, Cynthia Barcelon-Yang, Robert D. Reynolds, and Barry S. Brown pp 808 - 813; DOI: 10.1021/jm00360a005 |
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1-(Aminomethyl)-6,7-dihydroxytetralin derivatives: synthesis and assessment of dopamine-like effects Joseph G. Cannon, Zurilma Perez, John Paul Long, and Mustafa Ilhan pp 813 - 816; DOI: 10.1021/jm00360a006 |
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Recognition of cholinergic agonists by the muscarinic receptor. 1. Acetylcholine and other agonists with the NCCOCC backbone Jerome M. Schulman, Michael L. Sabio, and Raymond L. Disch pp 817 - 823; DOI: 10.1021/jm00360a007 |
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.alpha.-Adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic .alpha.2-adrenoreceptor antagonists and potential antidepressants Christopher B. Chapleo, Peter L. Myers, Richard C. M. Butler, John C. Doxey, Alan G. Roach, and Colin F. C. Smith pp 823 - 831; DOI: 10.1021/jm00360a008 |
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Synthesis of iodine-125 labeled (.+-.)-15-[4-azidobenzyl]carazolol: a potent .beta.-adrenergic photoaffinity probe Sarah L. Heald, Peter W. Jeffs, Thomas N. Lavin, Ponnal Nambi, Robert J. Lefkowitz, and Marc G. Caron pp 832 - 838; DOI: 10.1021/jm00360a009 |
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Quantitative aspects of the receptor binding of cytokinin agonists and antagonists Hajime Iwamura, Noboru Masuda, Koichi Koshimizu, and Satoshi Matsubara pp 838 - 844; DOI: 10.1021/jm00360a010 |
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Synthesis, benzodiazepine receptor binding, and anticonvulsant activity of 2,3-dihydro-3-oxo-5H-pyrido[3,4-b][1,4]benzothiazine-4-carbonitriles Robert J. Chorvat, Bipin N. Desai, Suzanne Evans Radak, James Bloss, James Hirsch, and Stanley Tenen pp 845 - 850; DOI: 10.1021/jm00360a011 |
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Quantitative structure-inotropy relationship applied to substituted grayanotoxins Naohiro Shirai, Jinsaku Sakakibara, Toyo Kaiya, Sawako Kobayashi, Yoshihiro Hotta, and Kazumi Takeya pp 851 - 855; DOI: 10.1021/jm00360a012 |
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Antihypertensive 9-substituted 1-0xa-4,9-diazaspiro[5.5]undecan-3-ones Robin D. Clark, Joan M. Caroon, David B. Repke, Arthur M. Strosberg, Susan M. Bitter, Marlys D. Okada, Anton D. Michel, and Roger L. Whiting pp 855 - 861; DOI: 10.1021/jm00360a013 |
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Oxidation of uric acid. 4. Synthesis, structure, and diabetogenic action of 5-imino-2,4,6(1H,3H,5H)-pyrimidinetrione salts and their alloxan-like covalent adducts Mirko Poje, Boris Rocic, Milan Sikirica, Ivan Vickovic, and Milenko Bruvo pp 861 - 864; DOI: 10.1021/jm00360a014 |
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1,3-Diaryltriazenes: a new class of anorectic agents David T. Hill, Kerry G. Stanley, Janice E. Karoglan Williams, Bernard Loev, Phillip J. Fowler, James P. McCafferty, Edward Macko, Charles E. Berkoff, and Christine B. Ladd pp 865 - 869; DOI: 10.1021/jm00360a015 |
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4'-Methylangelicins: new potential agents for the photochemotherapy of psoriasis Francesco Dall'Acqua, Daniela Vedaldi, Franco Bordin, Francarosa Baccichetti, Francesco Carlassare, Marisa Tamaro, Paolo Rodighiero, Giovanni Pastorini, Adriano Guiotto, and et al. pp 870 - 876; DOI: 10.1021/jm00360a016 |
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Synthesis and antitumor evaluation of selected 5,6-disubstituted 1(2)H-indazole-4,7-diones Gregory A. Conway, Larry J. Loeffler, and Iris H. Hall pp 876 - 884; DOI: 10.1021/jm00360a017 |
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Bleomycin analogs. Phenylthiazole models of the bithiazole moiety of bleomycin A2 James M. Riordan and Ted T. Sakai pp 884 - 891; DOI: 10.1021/jm00360a018 |
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3'-Amino-2',3'-dideoxyribonucleosides of some pyrimidines: synthesis and biological activities Thomas A. Krenitsky, G. Andrew Freeman, Sammy R. Shaver, Lowrie M. Beacham, Stuart Hurlbert, Naomi K. Cohn, Lynn P. Elwell, and John W. T. Selway pp 891 - 895; DOI: 10.1021/jm00360a019 |
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4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogs of THIP. Synthesis and biological activity Povl Krogsgaard-Larsen, Hans Mikkelsen, Poul Jacobsen, Erik Falch, David R. Curtis, Martin J. Peet, and John D. Leah pp 895 - 900; DOI: 10.1021/jm00360a020 |
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Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Jan J. Hansen, Joern Lauridsen, Elsebet Nielsen, and Povl Krogsgaard-Larsen pp 901 - 903; DOI: 10.1021/jm00360a021 |
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Synthesis of analogs of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin Daniel H. Rich and Francesco G. Salituro pp 904 - 910; DOI: 10.1021/jm00360a022 |
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Synthesis and biological properties of new hexapeptide substrates for vitamin K dependent carboxylase. Evidence for X-Pro cis/trans amide bond interconversions in prothrombin precursor fragment 18-23 Daniel H. Rich, Megumi Kawai, Hedda L. Goodman, and John W. Suttie pp 910 - 916; DOI: 10.1021/jm00360a023 |
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Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism Vijay K. Chadha, Kevin G. Leidal, and Bryce V. Plapp pp 916 - 922; DOI: 10.1021/jm00360a024 |
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Synthesis of thiazole-4-carboxamide adenine dinucleotide. A powerful inhibitor of IMP dehydrogenase Gulilat Gebeyehu, Victor E. Marquez, James A. Kelley, David A. Cooney, Hiremagalur N. Jayaram, and David G. Johns pp 922 - 925; DOI: 10.1021/jm00360a025 |
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Book Reviews pp 925 - 932; DOI: 10.1021/jm00360a600 |
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4-(Aminoalkyl)-7-hydroxy-2(3H)-indolones, a novel class of potent presynaptic dopamine receptor agonists William F. Huffman, Ralph F. Hall, Janet A. Grant, James W. Wilson, J. Paul Hieble, and Richard A. Hahn pp 933 - 935; DOI: 10.1021/jm00361a001 |
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Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindans Klaus P. Boegesoe pp 935 - 947; DOI: 10.1021/jm00361a002 |
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New selenium-75 labeled radiopharmaceuticals: selenonium analogs of dopamine Samy A. Sadek, Garo P. Basmadjian, Pan M. Hsu, and Joseph A. Rieger pp 947 - 950; DOI: 10.1021/jm00361a003 |
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.beta.1-Selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class John J. Baldwin, George H. Denny, Ralph Hirschmann, Mark B. Freedman, Gerald S. Ponticello, Dennis M. Gross, and Charles S. Sweet pp 950 - 957; DOI: 10.1021/jm00361a004 |
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Optically active catecholimidazolines: a study of steric interactions at .alpha.-adrenoreceptors Duane D. Miller, Akihiko Hamada, Edward C. Craig, Gary G. Christoph, Judith C. Galluci, Peter J. Rice, Jon W. Banning, and Popat N. Patil pp 957 - 963; DOI: 10.1021/jm00361a005 |
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Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 1. 1-[[p-[2-(Acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines Ernst H. Schweizer, Fritz Maerki, Claude Lehmann, and Henri Dietrich pp 964 - 970; DOI: 10.1021/jm00361a006 |
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Sulfonyliminoimidazolidines. A new class of oral hypoglycemia agents. 2. Mode of action and x-ray structure of 1-[[p-[2-(crotonylamine)ethyl]phenyl]sulfonyl]-3-cyclohexyl-2-iminoimidazolidine Ernst H. Schweizer, Fritz Maerki, and Grety Rihs pp 970 - 973; DOI: 10.1021/jm00361a007 |
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Synthesis and receptor binding studies relevant to the neuroleptic activities of some 1-methyl-4-piperidylidene-9-substituted-pyrrolo[2,1-b][3]benzazepine derivatives David C. Remy, Susan F. Britcher, Stella W. King, Paul S. Anderson, Cecilia A. Hunt, William C. Randall, Patrice Belanger, Joseph G. Atkinson, Yves Girard, and et al. pp 974 - 980; DOI: 10.1021/jm00361a008 |
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Novel tetracyclic spiropiperidines. 3. 1-Arylspiro[indoline-3,4'-piperidine]s as potential antidepressants Helen H. Ong, James A. Profitt, James Fortunato, Edward J. Glamkowski, Daniel B. Ellis, Harry M. Geyer, Jeffrey C. Wilker, and Harald Burghard pp 981 - 986; DOI: 10.1021/jm00361a009 |
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Synthesis and anticonvulsant activity of some tetracyclic indole derivatives James L. Stanton and Michael H. Ackerman pp 986 - 989; DOI: 10.1021/jm00361a010 |
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Theory and application of molecular potential energy fields in molecular shape analysis: a quantitative structure-activity relationship study of 2,4-diamino-5-benzylpyrimidines as dihydrofolate reductase inhibitors A. J. Hopfinger pp 990 - 996; DOI: 10.1021/jm00361a011 |
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Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines Arup K. Ghose and Gordon M. Crippen pp 996 - 1010; DOI: 10.1021/jm00361a012 |
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Substituent effects in cephalosporins as assessed by molecular orbital calculations, nuclear magnetic resonance, and kinetics Donald B. Boyd pp 1010 - 1013; DOI: 10.1021/jm00361a013 |
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A simplified high-pressure liquid chromatography method for determining lipophilicity for structure-activity relationships David A. Brent, Julie J. Sabatka, Douglas J. Minick, and David W. Henry pp 1014 - 1020; DOI: 10.1021/jm00361a014 |
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Phenylenebis(oxy)bis[2,2-dimethylpentanoic acids]: agents that elevate high-density lipoproteins Ila Sircar, M. Hoefle, and R. E. Maxwell pp 1020 - 1027; DOI: 10.1021/jm00361a015 |
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5-p-Benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase Linda Maggiora, Charles T. C. Chang, Mohamed E. Hasson, Christopher F. Bigge, and Mathias P. Mertes pp 1028 - 1036; DOI: 10.1021/jm00361a016 |
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Synthesis and monoamine oxidase inhibitory activities of .alpha.-allenic amines in vivo and in vitro. Different activities of two enantiomeric allenes Christer Sahlberg, Svante B. Ross, Ingrid Fagervall, Anna Lena Ask, and Alf Claesson pp 1036 - 1042; DOI: 10.1021/jm00361a017 |
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Synthesis and antiviral activity of distamycin A analogs: substitutions on the different pyrrole nitrogens and in the amidine function Leif Grehn, Ulf Ragnarsson, Bertil Eriksson, and Bo Oeberg pp 1042 - 1049; DOI: 10.1021/jm00361a018 |
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Analgesic narcotic antagonists. 15. Potent narcotic agonist 7-.beta.-arylalkyl-4,5.alpha.-epoxymorphinans Michael P. Kotick, David L. Leland, Joseph O. Polazzi, John F. Howes, and Ann Bousquet pp 1050 - 1056; DOI: 10.1021/jm00361a019 |
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2-(6-Carboxyhexyl)cyclopentanone hexylhydrazone. A potent and time-dependent inhibitor of platelet aggregation N. I. Ghali, D. L. Venton, S. C. Hung, and G. C. Le Breton pp 1056 - 1060; DOI: 10.1021/jm00361a020 |
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Interaction of conformationally flexible agonists with the active site of sweet taste. A study of arylureas M. R. Ciajolo, F. Lelj, T. Tancredi, P. A. Temussi, and A. Tuzi pp 1060 - 1065; DOI: 10.1021/jm00361a021 |
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Cloxacepride and related compounds: a new series of orally active antiallergic compounds Gunter Metz, M. H. Pindell, and H. L. Chen pp 1065 - 1070; DOI: 10.1021/jm00361a022 |
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Synthesis of hypoxanthine, guanine, and 6-thiopurine nucleosides of 6-deoxy-D-allofuranose Victor Nelson, Hassan S. El Khadem, Bertwell K. Whitten, and Debra Sesselman pp 1071 - 1074; DOI: 10.1021/jm00361a023 |
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Anticoccidial activity of 1-phenyluracils Max W. Miller and Larry R. Chappel pp 1075 - 1076; DOI: 10.1021/jm00361a024 |
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Synthesis and bacterial metabolism of cis- and trans-2-alkyl analogs of sodium cyclamate Robert A. Wiley, Daniel A. Pearson, Virginia Schmidt, Susan B. Wesche, and J. J. Roxon pp 1077 - 1079; DOI: 10.1021/jm00361a025 |
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Book Reviews pp 1080 - 1088; DOI: 10.1021/jm00361a600 |
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Synthesis and biological activity of prostaglandin lactones Gordon L. Bundy, D. C. Peterson, J. C. Cornette, W. L. Miller, C. H. Spilman, and J. W. Wilks pp 1089 - 1099; DOI: 10.1021/jm00362a001 |
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Synthesis of three potential inhibitors of leukotriene biosynthesis Juerg R. Pfister and D. V. Krishna Murthy pp 1099 - 1103; DOI: 10.1021/jm00362a002 |
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Quantitative structure-activity relationships employing independent quantum chemical indexes Istvan Lukovits pp 1104 - 1109; DOI: 10.1021/jm00362a003 |
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Ultra-short-acting .beta.-adrenergic receptor blocking agents. 3. Ethylenediamine derivatives of (aryloxy)propanolamines having esters on the aryl function Paul W. Erhardt, Chi M. Woo, William L. Matier, Richard J. Gorczynski, and William G. Anderson pp 1109 - 1112; DOI: 10.1021/jm00362a004 |
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Resolution and absolute configuration of an ergoline-related dopamine agonist, trans-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H(or 2H)-pyrazolo[3,4-g]quinoline Robert D. Titus, Edmund C. Kornfeld, Noel D. Jones, James A. Clemens, E. Barry Smalstig, Ray W. Fuller, Richard A. Hahn, Martin D. Hynes, Norman R. Mason, and et al. pp 1112 - 1116; DOI: 10.1021/jm00362a005 |
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Synthesis and biological properties of thiophene ring analogs of mianserin Jeffrey W. H. Watthey, Terrence Gavin, Mahesh Desai, Barbara M. Finn, Ronald K. Rodebaugh, and Steven L. Patt pp 1116 - 1122; DOI: 10.1021/jm00362a006 |
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Synthesis and antibacterial activity of some 3-[(alkylthio)methyl]quinoxaline 1-oxide derivatives John P. Dirlam, Joseph E. Presslitz, and B. J. Williams pp 1122 - 1126; DOI: 10.1021/jm00362a007 |
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Nitrogen bridgehead compounds. 33. New antiallergic 4H-pyrido[1,2-a]pyrimidin-4-ones. 2 Istvan Hermecz, Tibor Breining, Zoltan Meszaros, Jozsef Kokosi, Laszlo Meszaros, Franz Dessy, and Christine DeVos pp 1126 - 1130; DOI: 10.1021/jm00362a008 |
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Tricyclic triarylethylene antiestrogens: dibenz[b,f]oxepins, dibenzo[b,f]thiepins, dibenzo[a,e]cyclooctenes, and dibenzo[b,f]thiocins David Acton, George Hill, and Brian S. Tait pp 1131 - 1137; DOI: 10.1021/jm00362a009 |
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Ring-substituted 1,2-dialkylated 1,2-bis(hydroxyphenyl)ethanes. 1. Synthesis and estrogen receptor binding affinity of 2,2'- and 3,3'-disubstituted hexestrols Rolf W. Hartmann, Walter Schwarz, and Helmut Schoenenberger pp 1137 - 1144; DOI: 10.1021/jm00362a010 |
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Pyridazinones. 3. Synthesis, antisecretory, and antiulcer activities of 2-cyanoguanidine derivatives Toshihiro Yamada, Hiroshi Shimamura, Yoshitsugu Tsukamoto, Azuma Yamaguchi, and Masahiko Ohki pp 1144 - 1149; DOI: 10.1021/jm00362a011 |
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Mechanism of action of 2',5-difluoro-1-arabinosyluracil Akira Matsuda, Kyoichi A. Watanabe, and Jack J. Fox pp 1149 - 1152; DOI: 10.1021/jm00362a012 |
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Synthesis and biological evaluation of neutral derivatives of 5-fluoro-2'-deoxyuridine 5'-phosphate David Farquhar, Nancy J. Kuttesch, Michael G. Wilkerson, and Tammo Winkler pp 1153 - 1158; DOI: 10.1021/jm00362a013 |
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N-(4-Substituted-thiazolyl)oxamic acid derivatives, new series of potent, orally active antiallergy agents Karl D. Hargrave, Friedrich K. Hess, and James T. Oliver pp 1158 - 1163; DOI: 10.1021/jm00362a014 |
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Folate analogs. 22. Synthesis and biological evaluation of two analogs of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system M. G. Nair, Otha C. Salter, Roy L. Kisliuk, and Y. Gaumont pp 1164 - 1168; DOI: 10.1021/jm00362a015 |
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2-Haloethylating agents for cancer chemotherapy. 2-Haloethyl sulfonates Y. Fulmer Shealy, Charles A. Krauth, Robert F. Struck, and John A. Montgomery pp 1168 - 1173; DOI: 10.1021/jm00362a016 |
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5-Sulfamoylorthanilic acids, a sulfonamide series with salidiuretic activity K. Sturm, R. Muschaweck, and M. Hropot pp 1174 - 1187; DOI: 10.1021/jm00362a017 |
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A new class of nonhormonal pregnancy-terminating agents. Synthesis and contragestational activity of 3,5-diaryl-s-triazoles Amedeo Omodei-Sale, Pietro Consonni, and Giulio Galliani pp 1187 - 1192; DOI: 10.1021/jm00362a018 |
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Novel fluorinated antifolates. Enzyme inhibition and cytotoxicity studies on 2'- and 3'-fluoroaminopterin Jack Henkin and Wendy L. Washtien pp 1193 - 1196; DOI: 10.1021/jm00362a019 |
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Inhibitors of glycolic acid oxidase. 4-Substituted-2,4-dioxobutanoic acid derivatives H. W. R. Williams, E. Eichler, W. C. Randall, C. S. Rooney, E. J. Cragoe, K. B. Streeter, H. Schwam, S. R. Michelson, A. A. Patchett, and D. Taub pp 1196 - 1200; DOI: 10.1021/jm00362a020 |
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1,3-Dipalmitoylglycerol ester of chlorambucil as a lymphotropic, orally administrable antineoplastic agent Aaron Garzon-Aburbeh, Jacques H. Poupaert, Michel Claesen, Pierre Dumont, and Ghanem Atassi pp 1200 - 1203; DOI: 10.1021/jm00362a021 |
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Book Reviews pp 1204 - 1212; DOI: 10.1021/jm00362a600 |
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6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine: a potent and selective antagonist of .alpha.2-adrenoceptors Robert M. DeMarinis, J. Paul Hieble, and William D. Matthews pp 1213 - 1214; DOI: 10.1021/jm00363a001 |
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l-1,2,3,4-Tetrahydro-8-methoxy-5-(methylthio)-2-naphthalenamine: a potent and selective agonist at .alpha.1-adrenoceptors Robert M. DeMarinis and J. Paul Hieble pp 1215 - 1218; DOI: 10.1021/jm00363a002 |
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Gastric antisecretory 9H-xanthen-9-amines Paul E. Bender, Carl D. Perchonock, William G. Groves, Robert C. Smith Jr., Orum D. Stringer, Rayvon Sneed, Jack H. Schlosser, Linda S. Hostelley, Bruce Y. H. Hwang, and et al. pp 1218 - 1223; DOI: 10.1021/jm00363a003 |
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Structure-activity relations of convulsant and anticonvulsant barbiturates: a computer-graphic-based pattern-recognition analysis Peter R. Andrews, Lester C. Mark, David A. Winkler, and Graham P. Jones pp 1223 - 1229; DOI: 10.1021/jm00363a004 |
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Importance of carbon 6 chirality in conferring irreversible opioid antagonism to naltrexone-derived affinity labels L. M. Sayre, D. L. Larson, D. S. Fries, A. E. Takemori, and P. S. Portoghese pp 1229 - 1235; DOI: 10.1021/jm00363a005 |
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Ion-sensitive electrode potentiometry of organic anions: application to quantitative structure-activity relationships Roland F. Hirsch and Elliot M. Rachlin pp 1235 - 1239; DOI: 10.1021/jm00363a006 |
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Analogs of hycanthone and lucanthone as antitumor agents Sydney Archer, Abdel Hadi Zayed, Rabindra Rej, and Thomas A. Rugino pp 1240 - 1246; DOI: 10.1021/jm00363a007 |
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Structural studies of metyrapone: a potent inhibitor of cytochrome P-450 Miriam Rossi pp 1246 - 1252; DOI: 10.1021/jm00363a008 |
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Structural requirements of olefinic 5-substituted deoxyuridines for antiherpes activity John Goodchild, Roderick A. Porter, Robert H. Raper, Iain S. Sim, Roger M. Upton, Julie Viney, and Harry J. Wadsworth pp 1252 - 1257; DOI: 10.1021/jm00363a009 |
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Synthesis and antifilarial activity of N-[4-[[4-alkoxy-3-[(dialkylamino)methyl]phenyl]amino]-2-pyrimidinyl]-N'-phenylguanidines Mario Angelo, Daniel Ortwine, Donald Worth, Leslie M. Werbel, and John W. McCall pp 1258 - 1267; DOI: 10.1021/jm00363a010 |
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Angiotensin converting enzyme inhibitors: N-Substituted monocyclic and bicyclic amino acid derivatives James L. Stanton, Norbert Gruenfeld, Joseph E. Babiarz, Michael H. Ackerman, Robert C. Friedmann, Andrew M. Yuan, and William Macchia pp 1267 - 1277; DOI: 10.1021/jm00363a011 |
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Angiotensin converting enzyme inhibitors: 1-glutarylindoline-2-carboxylic acid derivatives Norbert Gruenfeld, James L. Stanton, Andrew M. Yuan, Frank H. Ebetino, Leslie J. Browne, Candido Gude, and Charles F. Huebner pp 1277 - 1282; DOI: 10.1021/jm00363a012 |
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Aromatic retinoic acid analogs. 2. Synthesis and pharmacological activity Marcia I. Dawson, Rebecca Chan, Peter D. Hobbs, Wanru Chao, and Leonard J. Schiff pp 1282 - 1293; DOI: 10.1021/jm00363a013 |
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New myocardial imaging agents: stabilization of radioiodine as a terminal vinyl iodide moiety on tellurium fatty acids F. F. Knapp, M. M. Goodman, A. P. Callahan, L. A. Ferren, G. W. Kabalka, and K. A. R. Sastry pp 1293 - 1300; DOI: 10.1021/jm00363a014 |
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A polymeric drug for treatment of inflammatory bowel disease Joseph P. Brown, Geoff V. McGarraugh, Thomas M. Parkinson, Robert E. Wingard, and Andrew B. Onderdonk pp 1300 - 1307; DOI: 10.1021/jm00363a015 |
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Heterocyclic oxyacetic acid diuretics: indazole, benzisothiazole, and benzisothiazole 1,1-dioxide analogs of [[7-chloro-3-(2-fluorophenyl)-1,2-benzisoxazol-6-yl]oxy]acetic acid Greogory M. Shutske, Richard C. Allen, Manfred F. Foersch, Linda L. Setescak, and Jeffrey C. Wilker pp 1307 - 1311; DOI: 10.1021/jm00363a016 |
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N2-1H-Benzimidazol-2-yl-N4-phenyl-2,4-pyrimidinediamines and N2-1H-benzimidazol-2-yl-5,6,7,8-tetrahydro-N4-phenyl-2,4-quinazolinediamines as potential antifilarial agents Mario M. Angelo, Daniel Ortwine, Donald F. Worth, and Leslie M. Werbel pp 1311 - 1316; DOI: 10.1021/jm00363a017 |
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Relationship between metabolism and radioprotective activity of 2-phenylthiazolidine and its m-bromo derivative J. P. Fernandez, Y. Robbe, J. P. Chapat, J. L. Chanal, M. Genin, H. Sentenac-Roumanou, and M. Fatome pp 1317 - 1319; DOI: 10.1021/jm00363a018 |
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Additional conformational data for the mapping of the progestin binding site: crystal structures of 21-(phenylseleno)progesterone and 17.alpha.-(phenylseleno)progesterone Evelyne Surcouf, Genevieve Lepicard, Jean Paul Mornon, Tiiu Ojasoo, and Jean Pierre Raynaud pp 1320 - 1323; DOI: 10.1021/jm00363a019 |
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N-(substituted-phenyl)-D-glycopyranosylamines and their O-acetyl derivatives as potential modifiers of the formation of glycosaminoglycans Lin Wang, Charles A. Maniglia, Sharon L. Mella, and Alan C. Sartorelli pp 1323 - 1326; DOI: 10.1021/jm00363a020 |
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Studies of N-hydroxy-N'-aminoguanidine derivatives by nitrogen-15 nuclear magnetic resonance spectroscopy and as ribonucleotide reductase inhibitors Anna W. Tai, Eric J. Lien, E. Colleen Moore, Yu Chun, and John D. Roberts pp 1326 - 1329; DOI: 10.1021/jm00363a021 |
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Aza analogs of lucanthone: synthesis and antitumor and bactericidal properties Martine Croisy-Delcey and Emile Bisagni pp 1329 - 1333; DOI: 10.1021/jm00363a022 |
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Synthesis, evaluation of chemical reactivity, and murine antineoplastic activity of 2-hydroxy-5-(3,4-dichlorophenyl)-6,7-bis(hydroxymethyl)-2,3-dihydro-1H-pyrrolizine bis(2-propylcarbamate) and 2-acyloxy derivatives as potential water-soluble prodrugs Wayne K. Anderson, Chiung Pin Chang, and Howard L. McPherson pp 1333 - 1338; DOI: 10.1021/jm00363a023 |
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Book Reviews pp 1338 - 1340; DOI: 10.1021/jm00363a600 |
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Different receptor sites mediate opioid agonism and antagonism P. S. Portoghese and A. E. Takemori pp 1341 - 1343; DOI: 10.1021/jm00364a001 |
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Role of substrate lipophilicity on the N-demethylation and type I binding of 3-O-alkylmorphine analogs Peter H. Duquette, Richard R. Erickson, and Jordan L. Holtzman pp 1343 - 1348; DOI: 10.1021/jm00364a002 |
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Aporphines. 50. Kinetics of solvolysis of N-(2-chloroethyl)norapomorphine, an irreversible dopamine receptor antagonist Steven A. Cohen and John L. Neumeyer pp 1348 - 1353; DOI: 10.1021/jm00364a003 |
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Substituted (2-phenoxyphenyl)acetic acids with antiinflammatory activity. 1 David C. Atkinson, Keith E. Godfrey, Bernard Meek, John F. Saville, and Michael R. Stillings pp 1353 - 1360; DOI: 10.1021/jm00364a004 |
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Substituted (2-phenoxyphenyl)acetic acids with antiinflammatory activity. 2 David C. Atkinson, Keith E. Godfrey, Peter L. Myers, Nigel C. Phillips, Michael R. Stillings, and Anthony P. Welbourn pp 1361 - 1364; DOI: 10.1021/jm00364a005 |
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Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines Arnold Brossi, Padam N. Sharma, Louise Atwell, Arthur E. Jacobson, Maria A. Iorio, Marisa Molinari, and Colin F. Chignell pp 1365 - 1369; DOI: 10.1021/jm00364a006 |
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1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1S-(3S,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyranon-3-yl)-3-methylbutyl]amino]-4S,5S-dihydroxy-6-oxo-3S-ammoniohexanoate Yukiji Shimojima and Hiroshi Hayashi pp 1370 - 1374; DOI: 10.1021/jm00364a007 |
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Synthesis and transport applications of 3-aminobicyclo[3,2,1]octane-3-carboxylic acids Halvor N. Christensen, Mary E. Handlogten, Jaydutt V. Vadgama, Elena De la Cuesta, Paloma Ballesteros, Gregorio G. Trigo, and Carmen Avendano pp 1374 - 1378; DOI: 10.1021/jm00364a008 |
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Potential antiatherosclerotic agents. 2. (Aralkylamino)- and (alkylamino)benzoic acid analogs of cetaben J. Donald Albright, Vern G. DeVries, Elwood E. Largis, Thomas G. Miner, Marvin F. Reich, Sheldon A. Schaffer, Robert G. Shepherd, and Janis Upeslacis pp 1378 - 1393; DOI: 10.1021/jm00364a009 |
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Potential antiatherosclerotic agents. 3. Substituted benzoic and nonbenzoic acid analogs of cetaben J. Donald Albright, Vern G. DeVries, Mila T. Du, Elwood E. Largis, Thomas G. Miner, Marvin F. Reich, and Robert G. Shepherd pp 1393 - 1411; DOI: 10.1021/jm00364a010 |
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Potential antiatherosclerotic agents. 4. [(Functionalized-alkyl)amino]benzoic acid analogs of cetaben Vern G. DeVries, Elwood E. Largis, Thomas G. Miner, Robert G. Shepherd, and Janis Upeslacis pp 1411 - 1421; DOI: 10.1021/jm00364a011 |
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Synthesis of 3,4-dihydro-4-oxoquinazoline derivatives as potential anticonvulsants Niteen A. Vaidya, C. H. Panos, A. Kite, W. Ben Iturrian, and C. DeWitt Blanton pp 1422 - 1425; DOI: 10.1021/jm00364a012 |
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Synthesis and antihypertensive activity of a series of spiro[1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine-2,5'-oxazolidin-2'-one]s Joan M. Caroon, Robin D. Clark, Arthur F. Kluge, Chi Ho Lee, and Arthur M. Strosberg pp 1426 - 1433; DOI: 10.1021/jm00364a013 |
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Synthesis and antihypertensive activity of some new quinazoline derivatives Erkki Honkanen, Aino Pippuri, Pekka Kairisalo, Pentti Nore, Heikki Karppanen, and Ilari Paakkari pp 1433 - 1438; DOI: 10.1021/jm00364a014 |
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Autoxidation of the antitumor drug 9-hydroxyellipticine and its derivatives Christian Auclair, Keith Hyland, and Claude Paoletti pp 1438 - 1444; DOI: 10.1021/jm00364a015 |
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Structure-activity studies of dermorphin. Synthesis and some pharmacological data of dermorphin and its 1-substituted analogs Krzysztof Darlak, Zbigniew Grzonka, Piotr Janicki, Andrzej Czlonkowski, and S. Witold Gumulka pp 1445 - 1447; DOI: 10.1021/jm00364a016 |
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Methotrexate analogs. 19. Enhancement of the antitumor effect of methotrexate and 3',5'-dichloromethotrexate by the use of lipid-soluble diesters A. Rosowsky and C. S. Yu pp 1448 - 1452; DOI: 10.1021/jm00364a017 |
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Mitomycin C analogs with secondary amines at position 7 Bhashyam S. Iyengar, Salah M. Sami, Shirley E. Tarnow, William A. Remers, William T. Bradner, and John E. Schurig pp 1453 - 1457; DOI: 10.1021/jm00364a018 |
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Inhibition of renin by angiotensinogen peptide fragments containing the hydroxy amino acid residue 5-amino-3-hydroxy-7-methyloctanoic acid Rodney L. Johnson and Karen Verschoor pp 1457 - 1462; DOI: 10.1021/jm00364a019 |
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Synthesis of aminomethyl-substituted cyclic imide derivatives for evaluation as anticonvulsants Eugene S. Stratford and Robert W. Curley pp 1463 - 1469; DOI: 10.1021/jm00364a020 |
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Multisubstrate adducts as potential inhibitors of S-adenosylmethionine dependent methylases: inhibition of indole N-methyltransferase by (5H-deoxyadenosyl)[3-(3-indolyl)propyl-1-yl]methylsulfonium and (5'-deoxyadenosyl)[4-(3-indolyl)but-1-yl]methylsulfonium salts Eric Benghiat and Peter A. Crooks pp 1470 - 1477; DOI: 10.1021/jm00364a021 |
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Adenosine deaminase inhibitors. Synthesis and biological evaluation of (.+-.)-3,6,7,8-tetrahydro-3-[(2-hydroxyethoxy)methyl]imidazo[4,5-d][1,3]diazepin-8-ol and some selected C-5 homologs of pentostatin H. D. Hollis Showalter, Sterling R. Putt, Pal E. Borondy, and Joan L. Shillis pp 1478 - 1482; DOI: 10.1021/jm00364a022 |
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Synthesis and biological evaluation of 2-fluoro-8-azaadenosine and related compounds John A. Montgomery, Anita T. Shortnacy, and John A. Secrist pp 1483 - 1489; DOI: 10.1021/jm00364a023 |
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Pyrazolo[3,4-d]pyrimidine ribonucleosides as anticoccidials. 3. Synthesis and activity of some nucleosides of 4-[(arylalkenyl)thio]pyrazolo[3,4-d]pyrimidines Janet L. Rideout, Thomas A. Krenitsky, Esther Y. Chao, Gertrude B. Elion, Raymond B. Williams, and Victoria S. Latter pp 1489 - 1494; DOI: 10.1021/jm00364a024 |
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Nitrogen bridgehead compounds. 38. New antiallergic 4H-pyrido[1,2-a]pyrimidin-4-ones. 3 Istvan Hermecz, Tibor Breining, Lelle Vasvari-Debreczy, Agnes Horvath, Zoltan Meszaros, Istvan Bitter, Christine DeVos, and Ludovic Rodriguez pp 1494 - 1499; DOI: 10.1021/jm00364a025 |
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Antiallergic agents. 2. N-(1H-Tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides Yasushi Honma, Kuniyuki Oda, Tomiki Hashiyama, Kyoji Hanamoto, Hideo Nakai, Hirozumi Inoue, Akihiko Ishida, Mikio Takeda, Yasutoshi Ono, and Kei Tsuzurahara pp 1499 - 1504; DOI: 10.1021/jm00364a026 |
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2,3-Dihydro-3-(1-pyrryl)spiro[benzofuran-2,4'-piperidine]s and 2,3-dihydro-3-(1-pyrryl)spiro[benzofuran-2,3'-pyrrolidine]s: novel antihypertensive agents Larry Davis, Marc N. Agnew, Richard C. Effland, Joseph T. Klein, Jan M. Kitzen, and Mary A. Schwenkler pp 1505 - 1510; DOI: 10.1021/jm00364a027 |
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9-Acridinyl and 2-methoxy-6-chloro-9-acridinyl derivatives of aliphatic di-, tri-, and tetraamines. Chemistry, cytostatic activity, and schistosomicidal activity John B. Hansen, Eyvind Langvad, Flemming Frandsen, and Ole Buchardt pp 1510 - 1514; DOI: 10.1021/jm00364a028 |
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Optical resolution, absolute configuration, and activity of the enantiomers of proxyphylline Kirsten Selvig, Merete Ruud-Christensen, and Arne J. Aasen pp 1514 - 1518; DOI: 10.1021/jm00364a029 |
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Design of anticandidal agents: synthesis and biological properties of analogs of polyoxin L Ponniah Shenbagamurthi, Herb A. Smith, Jeffrey M. Becker, Alvin Steinfeld, and Fred Naider pp 1518 - 1522; DOI: 10.1021/jm00364a030 |
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Synthesis and pH-dependent stability of purine-6-sulfenic acid, a putative reactive metabolite of 6-thiopurine R. T. Abraham, L. M. Benson, and I. Jardine pp 1523 - 1526; DOI: 10.1021/jm00364a031 |
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Synthesis and antitumor activity of 7- and 9-(6'-deoxy-.alpha.-L-talofuranosyl)-hypoxanthine and 9-(6'-deoxy-.alpha.-L-talofuranosyl)-6-thiopurine Victor Nelson and Hassan S. El Khadem pp 1527 - 1530; DOI: 10.1021/jm00364a032 |
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An evaluation of certain chain-extended analogs of 9-.beta.-D-arabinofuranosyladenine for antiviral and cardiovascular activity David G. Baker, Richard P. Crews, Theodore H. Haskell, Sterling R. Putt, Gussie Arnett, William M. Shannon, Michael Reinke, Namat B. Katlama, and John C. Drach pp 1530 - 1534; DOI: 10.1021/jm00364a033 |
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Potential tissue-imaging agents: 23-(trimethyl[117mSn]stannyl)-24-nor-5.alpha.-cholan-3.beta.-ol Furn F. Knapp, Alvin P. Callahan, Kathleen R. Ambrose, Leigh Ann Ferren, Thomas A. Butler, and Jack L. Coffey pp 1535 - 1537; DOI: 10.1021/jm00364a034 |
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Synthesis and evaluation of 24-(isopropyl[75Se]seleno)chol-5-en-3.beta.-ol F. F. Knapp, T. A. Butler, L. A. Ferren, A. P. Callahan, C. E. Guyer, and J. L. Coffey pp 1538 - 1541; DOI: 10.1021/jm00364a035 |
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Book Reviews pp 1541 - 1544; DOI: 10.1021/jm00364a600 |
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Effects of gonadotropin releasing hormone agonists and antagonists on reproductive functions Catherine Rivier, Wylie Vale, and Jean Rivier pp 1545 - 1550; DOI: 10.1021/jm00365a001 |
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.alpha.-(Fluoromethyl)dehydroornithine and .alpha.-(fluoromethyl)dehydroputrescine analogs as irreversible inhibitors of ornithine decarboxylase Philippe Bey, F. Gerhart, V. Van Dorsselaer, and C. Danzin pp 1551 - 1556; DOI: 10.1021/jm00365a002 |
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Synthesis and biological evaluation of sparsomycin analogs Scherer S. Duke and Marvin R. Boots pp 1556 - 1561; DOI: 10.1021/jm00365a003 |
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.beta.1-Selective adrenoceptor antagonists. 1. Synthesis and .beta.-adrenergic blocking activity of a series of binary (aryloxy)propanolamines R. W. Kierstead, A. Faraone, F. Mennona, J. Mullin, R. W. Guthrie, H. Crowley, B. Simko, and L. C. Blaber pp 1561 - 1569; DOI: 10.1021/jm00365a004 |
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.beta.1-Selective adrenoceptor antagonists. 2. 4-Ether-linked phenoxypropanolamines Peter J. Machin, David N. Hurst, Rachel M. Bradshaw, Leslie C. Blaber, David T. Burden, Allison D. Fryer, Rosemary A. Melarange, and Celia Shivdasani pp 1570 - 1576; DOI: 10.1021/jm00365a005 |
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Synthesis and substituent effects on antibacterial activity, alkaline hydrolysis rates, and infrared absorption frequencies of some cephem analogs related to latamoxef (moxalactam) Masayuki Narisada, Tadashi Yoshida, Mitsuaki Ohtani, Kiyoshi Ezumi, and Mamoru Takasuka pp 1577 - 1582; DOI: 10.1021/jm00365a006 |
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Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols John M. Evans, Charles S. Fake, Thomas C. Hamilton, Robert H. Poyser, and Eric A. Watts pp 1582 - 1589; DOI: 10.1021/jm00365a007 |
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2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents Eugene J. Trybulski, Louis E. Benjamin, James V. Earley, R. Ian Fryer, Norman W. Gilman, Earl Reeder, Armin Walser, Arnold B. Davidson, W. Dale Horst, and et al. pp 1589 - 1596; DOI: 10.1021/jm00365a008 |
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2-Benzazepines. 6. Synthesis and pharmacological properties of the metabolites of 9-chloro-7-(2-chlorophenyl)-5H-pyrimido[5,4-d][2]benzazepine Eugene J. Trybulski, R. Ian Fryer, Earl Reeder, Armin Walser, and John Blount pp 1596 - 1601; DOI: 10.1021/jm00365a009 |
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C4-Substituted 1-.beta.-D-ribofuranosylpyrazolo[3,4-d]pyrimidines as adenosine agonist analogs Harriet W. Hamilton and James A. Bristol pp 1601 - 1606; DOI: 10.1021/jm00365a010 |
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Potent antagonists of the antidiuretic responses to arginine-vasopressin based on modifications of [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid),2-D-phenylalanine,4-valine]arginine-vasopressin at position four Maurice Manning, Aleksandra Olma, Janny Seto, Wilbur H. Sawyer, and Wieslaw A. Klis pp 1607 - 1613; DOI: 10.1021/jm00365a011 |
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Synthesis of potential anticancer agents. Pyrido[4,3-b][1,4]oxazines and pyrido[4,3-b][1,4]thiazines Carroll Temple, Glynn P. Wheeler, Robert N. Comber, Robert D. Elliott, and John A. Montgomery pp 1614 - 1619; DOI: 10.1021/jm00365a012 |
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Potential antitumor agents. Part 38. 3-Substituted 5-carboxamido derivatives of amsacrine William A. Denny, Graham J. Atwell, and Bruce C. Baguley pp 1619 - 1625; DOI: 10.1021/jm00365a013 |
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Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: relationship to DNA binding and antitumor activity William A. Denny, Graham J. Atwell, and Bruce C. Baguley pp 1625 - 1630; DOI: 10.1021/jm00365a014 |
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Tetracyclic chromophoric analogs of actinomycin D: synthesis, structure elucidation and interconvertibility from one form to another, antitumor activity, and structure-activity relationships Sisir K. Sengupta, Madulla S. Madhavarao, Christine Kelly, and Joanne Blondin pp 1631 - 1637; DOI: 10.1021/jm00365a015 |
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Antagonists of slow-reacting substance of anaphylaxis. 1. Pyrido[2,1-b]quinazolinecarboxylic acid derivatives Jefferson W. Tilley, Paul Levitan, Ann F. Welton, and Herman J. Crowley pp 1638 - 1642; DOI: 10.1021/jm00365a016 |
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Synthesis and pharmacological characterization of (.+-.)-5,9.alpha.-dimethyl-2-[2-(4-fluorophenyl)ethyl]-2'-hydroxy-6,7-benzomorphan (fluorophen), a ligand suitable for visualization of opiate receptors in vivo Kenner C. Rice, P. Eric Konicki, Remi Quirion, Terrence R. Burke, and Candace B. Pert pp 1643 - 1645; DOI: 10.1021/jm00365a017 |
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Some biological properties of the impure dichloride salt of tetrakis[p-(dimethylamino)phenyl]ethylene and a pinacolone Gerald A. LePage, Richard M. Elofson, Karlo F. Schulz, James Laidler, Konstanty P. Kowalewski, Allan S. Hay, Robert J. Crawford, Dennis Tanner, and Reuben B. Sandin pp 1645 - 1647; DOI: 10.1021/jm00365a018 |
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Synthesis and antibacterial activities of new (.alpha.-hydrazinobenzyl)cephalosporins A. Balsamo, B. Macchia, F. Macchia, A. Rossello, R. Giani, G. Pifferi, M. Pinza, and G. Broccali pp 1648 - 1650; DOI: 10.1021/jm00365a019 |
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A deuterium isotope effect on the inhibition of gastric secretion by N,N-dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(4,6-dimethyl-2-pyridyl)urea. Synthesis of metabolites Jacob M. Hoffman, Charles N. Habecker, Adolph M. Pietruszkiewicz, William A. Bolhofer, Edward J. Cragoe, Mary Lou Torchiana, and Ralph Hirschmann pp 1650 - 1653; DOI: 10.1021/jm00365a020 |
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Synthesis and pharmacological activity of 6-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethen-1-yl)]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids Marcia I. Dawson, Rebecca L. S. Chan, Krzysztof Derdzinski, Peter D. Hobbs, Wan Ru Chao, and Leonard J. Schiff pp 1653 - 1656; DOI: 10.1021/jm00365a021 |
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An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level Robert J. Weinkam and M. Eileen Dolan pp 1656 - 1659; DOI: 10.1021/jm00365a022 |
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Antidiabetic activity of some 1-substituted 3,5-dimethylpyrazoles Raafat Soliman and Suzan A. S. Darwish pp 1659 - 1663; DOI: 10.1021/jm00365a023 |
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Book Reviews pp 1664 - 1666; DOI: 10.1021/jm00365a600 |
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Neurotransmitter receptor binding and drug discovery Solomon H. Snyder pp 1667 - 1672; DOI: 10.1021/jm00366a001 |
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Khellin analogs. 1. General topological requirements for lipid-altering activity in furochromones Ronald B. Gammill, Charles E. Day, and Paul E. Schurr pp 1672 - 1674; DOI: 10.1021/jm00366a002 |
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Structure-activity relationships for and potentiation of the antimitogenic activity of 2-5A core derived from 2-5A, a mediator of interferon action Paul F. Torrence, Jiro Imai, Krystyna Lesiak, Johan Warrinnier, Jan Balzarini, and Erik De Clercq pp 1674 - 1678; DOI: 10.1021/jm00366a003 |
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Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model Donald T. Witiak, Prabhakar L. Kamat, Debra L. Allison, Stephen M. Liebowitz, Ronald Glaser, Jane E. Holliday, Melvin L. Moeschberger, and Joseph P. Schaller pp 1679 - 1686; DOI: 10.1021/jm00366a004 |
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Synthesis and chromatographic separation of the glucuronides of R- and S-propranolol J. E. Oatis, J. P. Baker, J. R. McCarthy, and D. R. Knapp pp 1687 - 1691; DOI: 10.1021/jm00366a005 |
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Synthesis and biological activity of various 3'-azido and 3'-amino analogs of 5-substituted pyrimidine deoxyribonucleosides Tai Shun Lin, You Song Gao, and William R. Mancini pp 1691 - 1696; DOI: 10.1021/jm00366a006 |
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Pyridinylpiperazines, a new class of selective .alpha.2-adrenoceptor antagonists Walfred S. Saari, Wasyl Halczenko, Stella W. King, Joel R. Huff, James P. Guare Jr., Cecilia A. Hunt, William C. Randall, Paul S. Anderson, Victor J. Lotti, and et al. pp 1696 - 1701; DOI: 10.1021/jm00366a007 |
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Estrogen receptor binding and estrogenic/antiestrogenic effects of two new metabolites of nitromiphene, 2-[p-[2-nitro-1-(4-methoxyphenyl)-2-phenylvinyl]phenoxy]-N-ethylpyrrolidine Peter C. Ruenitz, Jerome R. Bagley, and Corwin M. Mokler pp 1701 - 1705; DOI: 10.1021/jm00366a008 |
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2-Phenylpyrazolo[1,5-a]pyrimidin-7-ones. A new class of nonsteroidal antiinflammatory drugs devoid of ulcerogenic activity Gabriella Auzzi, Fabrizio Bruni, Lucia Cecchi, Annarella Costanzo, Lorenzo Pecori Vettori, Renato Pirisino, Marina Corrias, Giovanni Ignesti, Grazia Banchelli, and Laura Raimondi pp 1706 - 1709; DOI: 10.1021/jm00366a009 |
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Synthesis of 3,6-bis(aminoalkoxy)acridines and their effect on the immune system Robert B. Angier, Ronald V. Citarella, Martin Damiani, Paul F. Fabio, Thomas L. Fields, Soon M. Kang, Yangi Lin, Howard F. Lindh, K. C. Murdock, and et al. pp 1710 - 1715; DOI: 10.1021/jm00366a010 |
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Heterocyclic quinones. 4. A new highly cytotoxic drug: 6,7-bis(1-aziridinyl)-5,8-quinazolinedione Jean Renault, Sylviane Giorgi-Renault, Michel Baron, Patrick Mailliet, Claude Paoletti, Suzanne Cros, and Emmanuelle Voisin pp 1715 - 1719; DOI: 10.1021/jm00366a011 |
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Methotrexate analogs. 20. Replacement of glutamate by longer-chain amino diacids: Effects on dihydrofolate reductase inhibition, cytotoxicity, and in vivo antitumor activity Andre Rosowsky, Ronald Forsch, Jack Uren, Michael Wick, A. Ashok Kumar, and James H. Freisheim pp 1719 - 1724; DOI: 10.1021/jm00366a012 |
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Transport of antimicrobial agents using peptide carrier systems: anticandidal activity of m-fluorophenylalanine-peptide conjugates William D. Kingsbury, Jeffrey C. Boehm, Rajanikant J. Mehta, and Sarah F. Grappel pp 1725 - 1729; DOI: 10.1021/jm00366a013 |
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Synthesis of a biologically active fluorescent muramyl dipeptide congener C. K. Hiebert, W. C. Kopp, H. B. Richerson, and C. F. Barfknecht pp 1729 - 1732; DOI: 10.1021/jm00366a014 |
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Chloroalanyl and propargylglycyl dipeptides. Suicide-substrate-containing antibacterials Kam Sing Cheung, Steven A. Wasserman, Edward Dudek, Stephen A. Lerner, and Michael Johnston pp 1733 - 1741; DOI: 10.1021/jm00366a015 |
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Antibacterially active substituted anilides of carboxylic and sulfonic acids Warner M. Linfield, Thomas J. Micich, Thomas J. Montville, John R. Simon, Ermellina B. Murray, and Raymond G. Bistline pp 1741 - 1746; DOI: 10.1021/jm00366a016 |
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Anilides related to substituted benzamides. Potential antipsychotic activity of N-(4-amino-5-chloro-2-methoxyphenyl)-1-(phenylmethyl)-4-piperidinecarboxamide Frank E. Blaney, Michael S. G. Clark, Derek V. Gardner, Michael S. Hadley, David Middleton, and Trevor J. White pp 1747 - 1752; DOI: 10.1021/jm00366a017 |
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Folate antagonists. 20. Synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylamino)methyl]-2,4-quinazolinediamines Edward F. Elslager, Judith L. Johnson, and Leslie M. Werbel pp 1753 - 1760; DOI: 10.1021/jm00366a018 |
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An extension of the f-fragment method for the calculation of hydrophobic constants (log P) of conformationally defined systems Michael A. Pleiss and Gary L. Grunewald pp 1760 - 1764; DOI: 10.1021/jm00366a019 |
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Synthesis of 3-hydroxy-3-cyclohexylbutyric acid derivatives. 1. Cyclic homologs of 3-hydroxy-3-methylglutaric acid Paolo Cozzi, Germano Carganico, and G. Orsini pp 1764 - 1766; DOI: 10.1021/jm00366a020 |
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Synthesis of 3-hydroxy-3-cyclohexylbutyric acid derivatives. 2. Cyclic analogs of mevalonic acid Germano Carganico, Paolo Cozzi, and Gaetano Orsini pp 1767 - 1769; DOI: 10.1021/jm00366a021 |
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.alpha.-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines Walfred S. Saari, Wasyl Halczenko, William C. Randall, and Victor J. Lotti pp 1769 - 1772; DOI: 10.1021/jm00366a022 |
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Parasympatholytic (anticholinergic) esters of the isomeric 2-tropanols. 2. Non-glycolates Edward R. Atkinson, Donna D. McRitchie-Ticknor, Louis S. Harris, Sydney Archer, Mario D. Aceto, J. Pearl, and F. P. Luduena pp 1772 - 1775; DOI: 10.1021/jm00366a023 |
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14.beta.-(2-bromoacetamido)morphine and 14.beta.-(2-bromoacetamido)morphinone Sydney Archer, Ahmad Seyed-Mozaffari, Peter Osei-Gyimah, Jean M. Bidlack, and Leo G. Abood pp 1775 - 1777; DOI: 10.1021/jm00366a024 |
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Resolution of etodolac and antiinflammatory and prostaglandin synthetase inhibiting properties of the enantiomers Christopher A. Demerson, Leslie G. Humber, Nedumparambil A. Abraham, Gunther Schilling, Rene R. Martel, and Cecil Pace-Asciak pp 1778 - 1780; DOI: 10.1021/jm00366a025 |
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N-Arylhydroxamic acid N,O-acyltransferase. Positional requirements for the substrate hydroxyl group R. Bruce Banks, Timothy J. Smith, and Patrick E. Hanna pp 1780 - 1784; DOI: 10.1021/jm00366a026 |
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S-Carbobenzoxyglutathione: a competitive inhibitor of mammalian glyoxalase II Y. R. Hsu and S. J. Norton pp 1784 - 1785; DOI: 10.1021/jm00366a027 |
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Synthesis and some pharmacological properties of [4-threonine,7-sarcosine]oxytocin, a peptide with high oxytocic potency, and of [4-threonine,7-N-methylalanine]oxytocin Zbigniew Grzonka, Bernard Lammek, Diana Gazis, and Irving L. Schwartz pp 1786 - 1787; DOI: 10.1021/jm00366a028 |
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O-Imino esters of N,N-bis(2-chloroethyl)phosphorodiamidic acid. Synthesis, x-ray structure determination, and anticancer evaluation Susan Marie Ludeman, Kai Liu Shao, Gerald Zon, Vicky L. Himes, Alan D. Mighell, Shozo Takagi, and Kazutaka Mizuta pp 1788 - 1790; DOI: 10.1021/jm00366a029 |
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Pyrimidine and triazine 3-oxide sulfates: a new family of vasodilators John M. McCall, James W. Aiken, Constance G. Chidester, Donald W. DuCharme, and Michael G. Wendling pp 1791 - 1793; DOI: 10.1021/jm00366a030 |
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Additions and Corrections - Potential Anti-trypanosomal Agents. 1,N2-Disubstituted 2-Amino-5-hydroxy-4-methylnaphthol[1,2-d]thiazolium Salts and Related Compounds Peter Ulrich, and Anthony Cerami pp 1794 - 1794; DOI: 10.1021/jm00366a600 |
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Additions and Corrections - 1,2-Dihydropyrido[3,4-b]pyrazines: Structure-Activity Relationships Carroll Temple, Jr., Glynn P. Wheeler, Robert D. Elliott, Jerry D. Rose, Robert N. Comber, and John A. Montgomery pp 1794 - 1794; DOI: 10.1021/jm00366a601 |
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Additions and Corrections - Buspirone Analogues. 1. Structure-Activity Relationships in a Series of N-Aryl- and Heteroarylpiperazine Derivatives. J. P. Yerich, D. L. Temple, Jr., J. S. New, Duncan P. Taylor, and L. A. Riblet pp 1794 - 1794; DOI: 10.1021/jm00366a602 |
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Book Reviews pp 1794 - 1796; DOI: 10.1021/jm00366a603 |